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Molecular biology has transformed the field of pathology by providing new insights into human diseases and new tools for the diagnosis and classification of disease. In Principles of Molecular Pathology, Anthony Killeen, md, phd, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecula...

Because molecular pathology has only recently emerged from the laboratory, many molecular pathology protocols are still to be found only in the primary literature. In Molecular Pathology Protocols, Anthony Killeen has assembled a collection of readily reproducible molecular pathology techniques that are either frequently performed or recognized for their significant diagnostic utility. Each method is described in step-by-step detail by a leadi...

Anthony Killeen, MD, PhD, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead t...

Anthony Killeen has assembled a collection of readily reproducible molecular pathology techniques that are either frequently performed or recognized for their significant diagnostic utility. Each method is described in step-by-step detail by a leading molecular pathologist or laboratory scientist who has developed it or used it extensively. These clinical laboratory techniques can be used for the diagnosis or monitoring of cancer, hematologica...

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The text opens with coverage of the basic concepts of molecular pathology, principles of genetics, and basic laboratory principles. The next chapters provide a review of inherited disorders, the molecular basis of cancer, and specific cancers both in solid tumors and in hematological malignancies. The final chapters cover specialized topics: pharmacogenetics, identity testing, and selected infectious organisms. All of this material has been co...